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Jagged 1 antibody [4A24]

Cat No. GTX52879

Host

Mouse

Clonality

Monoclonal

Clone Name

4A24

Isotype

IgG2

Application

WB, FACS, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
FACS 1:50 - 1:200
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Jagged-1

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

RRID

AB_2887808

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AGS , AGS1 , AHD , AWS , CD339 , HJ1 , JAG1 , JAGL1 , jagged 1 , Jagged 1 , Jagged1 , jagged canonical Notch ligand 1

Cellular Localization

Membrane

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

REVIEW

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SDS
PBS.pdf