GeneTex
  • Country / Location Selection

United States (US)

Jagged 1 antibody [4A24]

Cat No. GTX52879

Host

Mouse

Clonality

Monoclonal

Clone Name

4A24

Isotype

IgG2

Application

WB, FACS, Neutralizing/Inhibition

Reactivity

Human
Package
100 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:1000
FACS 1:50 - 1:200
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

500 μg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Human recombinant Jagged-1

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

AGS , AGS1 , AHD , AWS , CD339 , HJ1 , JAG1 , JAGL1 , jagged 1 , Jagged 1 , Jagged1 , jagged canonical Notch ligand 1

Cellular Localization

Membrane

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

REVIEW

There are currently no reviews for Jagged 1 antibody [4A24] (GTX52879). Be the first to share your experience with this product.
SDS
PBS.pdf