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Jagged 1 antibody

Anti-Jagged 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31607
Anti-Jagged 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31607
Anti-Jagged 1 antibody used in Western Blot (WB). GTX31607

Cat No. GTX31607

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($369)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

134 kDa. ( Note )

Positive Control

Human Spleen Tissue Slide , HeLa Cell Lysate

Product Note

At least two isoforms of JAG1 are known to exist; this antibody will detect both isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

JAG1 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human JAG1.The immunogen is located within the last 50 amino acids of JAG1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

jagged canonical Notch ligand 1 , AGS , AGS1 , AHD , AWS , CD339 , DCHE , HJ1 , JAGL1

Cellular Localization

Membrane; Single-pass type I membrane protein

Background

The jagged 1 protein encoded by JAG1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the jagged 1 protein cause Alagille syndrome. Jagged 1 signalling through notch 1 has also been shown to play a role in hematopoiesis. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Jagged 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31607

GTX31607 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31607 Jagged 1 antibody.
Working concentration : 5 μg/ml

Anti-Jagged 1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31607

GTX31607 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31607 Jagged 1 antibody.
Working concentration : 20 μg/ml

Anti-Jagged 1 antibody used in Western Blot (WB). GTX31607

GTX31607 WB Image

WB analysis of HeLa cell lysate using GTX31607 Jagged 1 antibody.
Working concentration : 1 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf