GeneTex
United States (US)

K-Ras antibody

GTX32694_20180530_WB_18121410_253.jpg

Cat No. GTX32694

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200 - 1:500
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Specificity/Sensitivity

This antibody may cross react with N-Ras and H-Ras proteins.
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant protein of human KRAS

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Kras Proto-Oncogene, Gtpase,C-K-Ras,Cfc2,K-Ras2A,K-Ras2B,K-Ras4A,K-Ras4B,K-Ras,Ki-Ras,Kras1,Kras2,Ns,Ns3,Rald,Rask2,C-Ki-Ras2,Kras

Background

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX32694_20180530_WB_18121410_253.jpg

GTX32694 WB Image

WB analysis of various samples using GTX32694 K-Ras antibody.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 329