GeneTex
United States (US)

KCNA10 antibody

GTX16755_WB_18121410_497.jpg

Cat No. GTX16755

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

58 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide (C)KDPETLLPTNDIHR, corresponding to amino acid residues 187- 200 of human KV1.8 (Accession Q16322). Intracellular, N-terminus.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Voltage-Gated Channel Subfamily A Member 10,Kcn1,Kv1.8,Kcna10

Background

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16755_WB_18121410_497.jpg

GTX16755 WB Image

Anti-KV1.8 - Western blot analysis of rat (lanes 1 and 3) and mouse (lanes 2 and 4) heart lysates: 1-2. Anti-KV1.8 antibody, (1:800). 3-4. Anti-KV1.8 antibody, preincubated with the control peptide antigen.

Package List Price ($)
$ 329