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KCNAB2 antibody, Internal

Anti-KCNAB2 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47629
Anti-KCNAB2 antibody, Internal used in Western Blot (WB). GTX47629

Cat No. GTX47629

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
50 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

41 kDa. ( Note )

Positive Control

Jurkat

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human KCNAB2

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

potassium voltage-gated channel subfamily A regulatory beta subunit 2 , AKR6A5 , HKvbeta2 , HKvbeta2.1 , HKvbeta2.2 , KCNA2B , KV-BETA-2

Cellular Localization

Cytoplasm,Membrane,Cell membrane,Cytoplasm, cytoskeleton

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member is one of the beta subunits, which are auxiliary proteins associating with functional Kv-alpha subunits. This member alters functional properties of the KCNA4 gene product. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES

Anti-KCNAB2 antibody, Internal used in IHC (Paraffin sections) (IHC-P). GTX47629

GTX47629 IHC-P Image

IHC-P analysis of human heart tissue using GTX47629 KCNAB2 antibody at 1:600. Left to right : DAPI, Rabbit IgG, Merge. Low pH, heat-induced antigen retrieval method utilizing Sodium Citrate buffer was performed.

Anti-KCNAB2 antibody, Internal used in Western Blot (WB). GTX47629

GTX47629 WB Image

WB analysis of Jurkat cells using GTX47629 KCNAB2 antibody at 0.2-1μg/ml.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf