GeneTex
United States (US)

KCND1 antibody

GTX16691_WB_18121410_128.jpg
GTX16691_WB_1_18121410_288.jpg

Cat No. GTX16691

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

71 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide (C)KRRAIRLANSTAS, corresponding to amino acid residues 538-550 of human Kv4.1 (Accession Q9NSA2 ). Intracellular, C-terminal domain.

Purification

Affinity purified on immobilized peptide.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Voltage-Gated Channel Subfamily D Member 1,Kv4.1,Kcnd1

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This gene is expressed at moderate levels in all tissues analyzed, with lower levels in skeletal muscle. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16691_WB_18121410_128.jpg

GTX16691 WB Image

Anti-KV4.1 - Western blot analysis of rat brain lysate: 1. Anti-KV4.1 antibody, (1:400). 2. Anti- KV4.1 antibody, preincubated with the control peptide antigen.

GTX16691_WB_1_18121410_288.jpg

GTX16691 WB Image

Anti-KV4.1 - Western blot analysis of human neuroblastoma cell line SH-SY5Y (lanes 1 and 3) and mouse brain lysate (lanes 2 and 4): 1, 2. Anti-KV4.1 antibody, (1:400). 3, 4. Anti-KV4.1 antibody, preincubated with the control peptide antigen.

Package List Price ($)
$ 329