APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Dog, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.025% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide (C)RSRKVDKRSDPYH, corresponding to amino acid residues 81-93 (Intracellular, C-terminal part) of human KCNE3 (Accession : Q9Y6H6).
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
potassium voltage-gated channel subfamily E regulatory subunit 3 , BRGDA6 , HOKPP , HYPP , MiRP2
Cellular Localization
Cell membrane,Cytoplasm,Cell projection, dendrite
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX16690 WB Image
WB analysis of rat kidney (lanes 1 and 3) and heart (lanes 2 and 4) membrane lysates using GTX16690 KCNE3 antibody preincubated with or without immunogen peptide. Dilution : 1:200
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REFERENCE
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REVIEW
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