GeneTex
United States (US)

KCNG4 antibody

GTX106058_40835_IHC_M_19011506_465.jpg
GTX106058_42914_20170713_WB_19011506_217.jpg
GTX106058_40835_IHC_19011506_434.jpg

Cat No. GTX106058

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

59 kDa. ( Note )

Positive Control

PC-3

Predict Reactivity

Rat(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.58mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human KCNG4. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

KV6.3 antibody, KV6.4 antibody, MGC129609 antibody, MGC4558 antibody, KCNG4 antibody, voltage-gated potassium channel Kv6.3 antibody, voltage-gated potassium channel subunit Kv6.4 antibody, potassium voltage-gated channel subfamily G member 4 antibody, "potassium voltage-gated channel, subfamily G, member 4 antibody"

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX106058_40835_IHC_M_19011506_465.jpg

GTX106058 IHC-P Image

Immunohistochemical analysis of paraffin-embedded mouse testis, using KCNG4(GTX106058) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX106058_42914_20170713_WB_19011506_217.jpg

GTX106058 WB Image

Whole cell extract (30 µg) was separated by 10% SDS-PAGE, and the membrane was blotted with KCNG4 antibody (GTX106058) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

GTX106058_40835_IHC_19011506_434.jpg

GTX106058 IHC-P Image

Immunohistochemical analysis of paraffin-embedded BT483 xenograft, using KCNG4(GTX106058) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

SDS
PBS.pdf
Glycerol.pdf
Proclin.pdf