GeneTex
United States (US)

KCNH6 antibody

GTX16688_WB_18121410_145.jpg
GTX16688_IHC_18121410_564.jpg

Cat No. GTX16688

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC
Reactivity Human, Mouse, Rat
APPLICATION

Calculated MW

110 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide TLNFVEFNLEKHRS(C), corresponding to amino acid residues 185-198 of human Kv11.2 (Accession Q9H252). Intracellular, N-terminal part.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Voltage-Gated Channel Subfamily H Member 6,Erg-2,Erg2,Herg2,Kv11.2,Herg-2,Kcnh6

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16688_WB_18121410_145.jpg

GTX16688 WB Image

Anti-KV11.2_(erg2) - Western blot analysis of rat brain (1 and 3) and rat cortex ( 2 and 4) lysate: 1, 2. Anti-Kv11.2 (erg2) antibody, (1:200). 3, 4. Anti-Kv11.2 (erg2) antibody, preincubated with the control peptide antigen.

GTX16688_IHC_18121410_564.jpg

GTX16688 IHC Image

Anti-KV11.2_(erg2) - Expression of KV11.2 in rat hippocampus Immunohistochemical staining of Kv11.2 in rat hippocampus using Anti-Kv11.2 (erg2) antibody. A. Kv11.2 appears as diffuse staining (green) that defines the boundary of the reticular nucleus of thalamus (arrow). B. Staining with mouse anti-parvalbumin (PV, red) demonstrates both neuronal and diffuse staining. C. Confocal merge of KV11.2 and PV demonstrates overlap of the two markers labeling the reticular nucleus of the thalamus (orange).

Package List Price ($)
$ 329