GeneTex

  • Country / Location Selection

United States (US)

KCNK4 antibody

Anti-KCNK4 antibody used in Western Blot (WB). GTX16684
Anti-KCNK4 antibody used in Western Blot (WB). GTX16684
Anti-KCNK4 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16684

Cat. No. GTX16684

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-Fr

Reactivity

 Human, Mouse, Rat
Package
50 μl ($639)
See all KCNK4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-Fr Assay dependent
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.025% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide NLAFIDESSDTQSERGC, corresponding to amino acid residues 343-359 (Intracellular, C-terminus) of human KCNK4 (Accession  : Q9NYG8).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium two pore domain channel subfamily K member 4 , K2p4.1 , TRAAK , TRAAK1

Cellular Localization

Cell membrane

Background

This gene encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The encoded protein homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. This protein is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802. [provided by RefSeq, Nov 2015]

Database

Research Area

DATA IMAGES

Anti-KCNK4 antibody used in Western Blot (WB). GTX16684

GTX16684 WB Image

WB analysis of HEK-293-KCNK4  transfected cell lysates using GTX16684 KCNK4 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-KCNK4 antibody used in Western Blot (WB). GTX16684

GTX16684 WB Image

WB analysis of rat cerebellum lysate using GTX16684 KCNK4 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-KCNK4 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16684

GTX16684 IHC-Fr Image

IHC-Fr analysis of rat cerebellum tissue using GTX16684 KCNK4 antibody.
Panel A : KCNK4 channel appears in Purkinje neuronal processes (red).
Panel B : Staining of Purkinje nerve cells with mouse anti-calbindin D28K (a calcium binding protein, green).
Panel C : Merge of KCNK4 channel and calbindin D28K demonstrates the co-localization of these proteins.

REFERENCE

There are currently no references for KCNK4 antibody (GTX16684). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for KCNK4 antibody (GTX16684). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639