GeneTex
United States (US)

KCNMB1 antibody [N1C3]

GTX105666_40142_WB_M_heart_19011506_855.jpg
GTX105666_WB_19011506_561.jpg

Cat No. GTX105666

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000-1:10000
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse heart

Predict Reactivity

Rat, Rabbit, Bovine, Dog, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human KCNMB1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 1,Bkbeta1,K(Vca)Beta,Slo-Beta,Hbeta1,Hslo-Beta,K(Vca)Beta-1,Slo-Beta-1,Kcnmb1

Cellular Localization

Membrane; Multi-pass membrane protein

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX105666_40142_WB_M_heart_19011506_855.jpg

GTX105666 WB Image

Sample (50 ug of whole cell lysate)
A: mouse heart
12% SDS PAGE
GTX105666 diluted at 1:10000

GTX105666_WB_19011506_561.jpg

GTX105666 WB Image

Sample (30 ug of whole cell lysate)
A: A431 (GTX27909)
B: H1299
12% SDS PAGE
GTX105666 diluted at 1:1000

REFERENCE
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169