GeneTex
United States (US)

KCNMB2 antibody

GTX16645_WB_18121410_590.jpg
GTX16645_IHC_18121410_786.jpg

Cat No. GTX16645

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC
Reactivity Human, Rat
APPLICATION

Calculated MW

27 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Peptide (C)RHDEKRNIYQKIRDHDLLD, corresponding to amino acid residues 14-32 of human sloβ2 (Accession Q9Y691). Intracellular, N-terminal part.

Purification

Affinity purified on immobilized antigen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Calcium-Activated Channel Subfamily M Regulatory Beta Subunit 2,Kcnmb2

Background

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which decreases the activation time of MaxiK alpha subunit currents. Two variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX16645_WB_18121410_590.jpg

GTX16645 WB Image

Anti-slobeta2_(KCNMB2) - Western blot analysis of rat kidney (lanes 1 and 3) and rat heart (lanes 2 and 4) membranes: 1, 2. Anti-sloβ2 (KCNMB2) antibody, (1:200). 3, 4. Anti-sloβ2 (KCNMB2) antibody, preincubated with the control peptide antigen.

GTX16645_IHC_18121410_786.jpg

GTX16645 IHC Image

Anti-slobeta2_(KCNMB2) - Expression of slobeta2 in rat hippocampus Immunohistochemical staining of rat hippocampus using Anti-sloβ2 (KCNMB2). A. sloβ2 appears in the pyramidal layer (green). B. Staining of interneurons with mouse anti parvalbumin (PV, red). C. Confocal merge of sloβ2 and PV demonstrates presence of sloβ2 also in PV (GABA containing) cells (orange).

Package List Price ($)
$ 329