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KCNN2 antibody, C-term

Anti-KCNN2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX49068
Anti-KCNN2 antibody, C-term used in Western Blot (WB). GTX49068
Anti-KCNN2 antibody, C-term used in Western Blot (WB). GTX49068
Anti-KCNN2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX49068

Cat No. GTX49068

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Rat, Rhesus Monkey
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

64 kDa. ( Note )

Positive Control

HepG2 , human fetal liver

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a C-terminal region of Human KCNN2.

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

potassium calcium-activated channel subfamily N member 2 , KCa2.2 , SK2 , SKCA2 , SKCa 2 , hSK2

Cellular Localization

Membrane; Multi-pass membrane protein

Background

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]

Database

Research Area

DATA IMAGES

Anti-KCNN2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX49068

GTX49068 IHC-P Image

IHC-P analysis of Rhesus macaque spinal cord tissue using GTX49068 KCa2.2 antibody at 1:300.

Anti-KCNN2 antibody, C-term used in Western Blot (WB). GTX49068

GTX49068 WB Image

WB analysis of human fetal liver tissue using GTX49068 KCa2.2 antibody at 1μg/ml.

Anti-KCNN2 antibody, C-term used in Western Blot (WB). GTX49068

GTX49068 WB Image

WB analysis of HepG2 cells using GTX49068 KCa2.2 antibody at 1.25μg/ml.

Anti-KCNN2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX49068

GTX49068 IHC-P Image

IHC-P analysis of rat brain tissue using GTX49068 KCa2.2 antibody at 1:500.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319