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KCNQ1 antibody [5E12]

Anti-KCNQ1 antibody [5E12] used in Western Blot (WB). GTX60528
Anti-KCNQ1 antibody [5E12] used in ELISA (ELISA). GTX60528
Anti-KCNQ1 antibody [5E12] used in Flow cytometry (FACS). GTX60528
Anti-KCNQ1 antibody [5E12] used in Western Blot (WB). GTX60528

Cat. No. GTX60528

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5E12

Isotype

 IgG2b

Application

 WB, FACS, ELISA

Reactivity

 Human
Package
100 μl ($409)
See all KCNQ1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1/500 - 1/2000
FACS 1/200 - 1/400
ELISA 1/10000
Not tested in other applications.

Calculated MW

75 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Ascites

Preservative

0.03% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Purified recombinant fragment of human KCNQ1 expressed in E. Coli.

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily Q member 1 , ATFB1 , ATFB3 , JLNS1 , KCNA8 , KCNA9 , KVLQT1 , Kv1.9 , Kv7.1 , LQT , LQT1 , RWS , SQT2 , WRS

Cellular Localization

Cell membrane,Endoplasmic reticulum

Background

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-KCNQ1 antibody [5E12] used in Western Blot (WB). GTX60528

GTX60528 WB Image

WB analysis of human KCNQ1 (AA: 229-347) recombinant protein using GTX60528 KCNQ1 antibody [5E12].

Anti-KCNQ1 antibody [5E12] used in ELISA (ELISA). GTX60528

GTX60528 ELISA Image

ELISA analysis of antigen using GTX60528 KCNQ1 antibody [5E12].
Black : Control antigen 100ng
Purple : Antigen 10ng
Blue : Antigen 50ng
Red : Antigen 100ng

Anti-KCNQ1 antibody [5E12] used in Flow cytometry (FACS). GTX60528

GTX60528 FACS Image

FACS analysis of MCF-7 cells using GTX60528 KCNQ1 antibody [5E12].
Green : KCNQ1
Red : negative control

Anti-KCNQ1 antibody [5E12] used in Western Blot (WB). GTX60528

GTX60528 WB Image

WB analysis of MCF-7 (1) and A431 (2) cell lysate using GTX60528 KCNQ1 antibody [5E12].

REFERENCE

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REVIEW

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SDS
Sodium Azide.pdf
Package List Price ($)
$ 409