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KCNQ1 antibody [S37A-10]

Anti-KCNQ1 antibody [S37A-10] used in Western Blot (WB). GTX41988
Anti-KCNQ1 antibody [S37A-10] used in Western Blot (WB). GTX41988

Cat. No. GTX41988

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 S37A-10

Isotype

 IgG1

Application

 WB, IP, IHC

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all KCNQ1 products

APPLICATION

Application Note

We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).

Calculated MW

75 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein amino acids 2-101 of human KCNQ1, accession number P51787

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily Q member 1 , ATFB1 , ATFB3 , JLNS1 , KCNA8 , KCNA9 , KVLQT1 , Kv1.9 , Kv7.1 , LQT , LQT1 , RWS , SQT2 , WRS

Cellular Localization

Cell membrane , Endoplasmic reticulum

Background

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES

Anti-KCNQ1 antibody [S37A-10] used in Western Blot (WB). GTX41988

GTX41988 WB Image

Western blot analysis of KCNQ1 in a human cell line mix using a 1:1000 dilution of GTX41988.

Anti-KCNQ1 antibody [S37A-10] used in Western Blot (WB). GTX41988

GTX41988 WB Image

Western blot analysis of KCNQ1 in T-Cho cells using a 1:1000 dilution of GTX41988.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 399