GeneTex
United States (US)

KCNQ1 antibody

GTX64507_20180530_WB_18121411_751.jpg

Cat No. GTX64507

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
See all KCNQ1 products
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
Not tested in other applications.

Calculated MW

75 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant funsion protein containing a sequence corresponding to amino acids 250-549 of human KCNQ1 (NP_861463.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

ATFB3 Antibody , KCNA9 Antibody , RWS Antibody , SQT2 Antibody , KV7.1 Antibody , KCNA8 Antibody , WRS Antibody , JLNS1 Antibody , ATFB1 Antibody , KVLQT1 Antibody , LQT Antibody , KV1.9 Antibody , LQT1 Antibody

Background

This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]

Database

Research Area

DATA IMAGES
GTX64507_20180530_WB_18121411_751.jpg

GTX64507 WB Image

WB analysis of various samples using GTX64507 KCNQ1 antibody.
Dilution : 1:1000
Loading : 25μg per lane
Package List Price ($)
$ 319