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KCNQ2 antibody

Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891
Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891
Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891

Cat No. GTX82891

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P, IHC-Fr

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF 0.5 μg/ml
IHC-P Assay dependent
IHC-Fr 0.5 μg/ml
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Product Note

This antibody is specific for KCNQ2 and does not detect KCNQ1, KCNQ3, KCNQ4 or KCNQ5.

PROPERTIES

Form

Liquid

Buffer

PBS, 1mg/ml BSA

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

GST fusion protein encoding the first 70 amino acids of human KCNQ2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

potassium voltage-gated channel subfamily Q member 2 , BFNC , EBN , EBN1 , ENB1 , HNSPC , KCNA11 , KV7.2

Cellular Localization

Cell membrane

Background

The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891

GTX82891 ICC/IF Image

ICC/IF analysis of U251 cells using GTX82891 KCNQ2 antibody. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:20 overnight at 4ºC

Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891

GTX82891 ICC/IF Image

ICC/IF analysis of HepG2 cells using GTX82891 KCNQ2 antibody. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:100 overnight at 4 ºC

Anti-KCNQ2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX82891

GTX82891 ICC/IF Image

ICC/IF analysis of C6 cells using GTX82891 KCNQ2 antibody. Cells were probed without (right) or with(left) an antibody.
Green : Primary antibody
Blue : Nuclei
Red : Actin
Fixation : formaldehyde
Dilution : 1:100 overnight at 4 ºC

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339