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KCNQ4 antibody, Internal

Anti-KCNQ4 antibody, Internal used in Western Blot (WB). GTX49069
Anti-KCNQ4 antibody, Internal used in Western Blot (WB). GTX49069

Cat No. GTX49069

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB

Reactivity

Human, Hamster
Package
50 μg ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
Not tested in other applications.

Calculated MW

77 kDa. ( Note )

Positive Control

CHO , HT1080

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to an Internal region of Human KCNQ4.

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

potassium voltage-gated channel subfamily Q member 4 , DFNA2 , DFNA2A , KV7.4

Background

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KCNQ4 antibody, Internal used in Western Blot (WB). GTX49069

GTX49069 WB Image

WB analysis of HT1080 cells using GTX49069 Kv7.4 antibody at 0.2-1μg/ml.

Anti-KCNQ4 antibody, Internal used in Western Blot (WB). GTX49069

GTX49069 WB Image

WB analysis of CHO cells using GTX49069 Kv7.4 antibody at 1:1000.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf