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KCNQ4 antibody [S43-6]

Anti-KCNQ4 antibody [S43-6] used in Western Blot (WB). GTX41990
Anti-KCNQ4 antibody [S43-6] used in IHC (Frozen sections) (IHC-Fr). GTX41990

Cat. No. GTX41990

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 S43-6

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-Fr, IP

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all KCNQ4 products

APPLICATION

Application Note

We recommend a working dilution of 1-10ug/mL (WB), 0.1-1.0ug/mL (Perox) (IHC/ICC), 1.0-10ug/mL (IF).

Calculated MW

77 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein amino acids 2-77 of human KCNQ4, accession number P56696

Purification

Protein G Purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily Q member 4 , DFNA2 , DFNA2A , KV7.4

Background

The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KCNQ4 antibody [S43-6] used in Western Blot (WB). GTX41990

GTX41990 WB Image

Western blot analysis of KCNQ4 in rat tissue lysates using a 1:1000 dilution of GTX41990.

Anti-KCNQ4 antibody [S43-6] used in IHC (Frozen sections) (IHC-Fr). GTX41990

GTX41990 IHC-Fr Image

IHC analysis of KCNQ4 in frozen sections of mouse brain extract using GTX41990

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Package List Price ($)
$ 399