GeneTex
United States (US)

KCNQ5 antibody [N3C2], Internal

GTX106198_WB_19011506_210.jpg

Cat No. GTX106198

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

102 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLaS3

Predict Reactivity

Mouse, Rat, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.45mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human KCNQ5. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Kv7.5 antibody, KCNQ5 antibody, potassium channel protein antibody, voltage-gated potassium channel subunit Kv7.5 antibody, potassium channel subunit alpha KvLQT5 antibody, potassium voltage-gated channel subfamily KQT member 5 antibody, KQT-like 5 antibody, "potassium voltage-gated channel, KQT-like subfamily, member 5 antibody"

Cellular Localization

Membrane; Multi-pass membrane protein

Background

This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of only one has been determined. [provided by RefSeq]

Database

Research Area

DATA IMAGES
GTX106198_WB_19011506_210.jpg

GTX106198 WB Image

Sample(30 μg of whole cell lysate)
A:293T
7.5% SDS PAGE
GTX106198 diluted at 1:500

SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169