GeneTex
United States (US)

KDM4B antibody

JHD3B-antibody-GTX87868-IHC-1_18121411_623.jpg

Cat No. GTX87868

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

121 kDa. ( Note )

Specificity/Sensitivity

JHD3B Antibody detects endogenous levels of total KDM4B protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 106% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human KDM4B.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

EC1.14.11., JHD3B, Jumonji domain containing protein 2B, Jumonji domain containing protein2B, JMJ2B, EC 1.14.11., EC 1.14.11.-

Background

Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
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Database

DATA IMAGES
JHD3B-antibody-GTX87868-IHC-1_18121411_623.jpg

GTX87868 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human brain, using JHD3B Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339