*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
JHD3B Antibody detects endogenous levels of total KDM4B protein.
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 106% glycerol.
The antiserum was produced against synthesized peptide derived from human KDM4B.
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
EC1.14.11., JHD3B, Jumonji domain containing protein 2B, Jumonji domain containing protein2B, JMJ2B, EC 1.14.11., EC 1.14.11.-
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
GTX87868 IHC-P Image
Immunohistochemistry analysis of paraffin-embedded human brain, using JHD3B Antibody. The picture on the right is treated with the synthesized peptide.