GeneTex

  • Country / Location Selection

United States (US)

KDM5B antibody

Anti-KDM5B antibody used in IHC (Paraffin sections) (IHC-P). GTX60284

Cat. No. GTX60284

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P

Reactivity

 Human, Rat
Package
100 μl ($399)
See all KDM5B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-400
Not tested in other applications.

Calculated MW

176 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human KDM5B(80-130).

Purification

Protein A purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

lysine demethylase 5B , CT31 , JARID1B , MRT65 , PLU-1 , PLU1 , PPP1R98 , PUT1 , RBBP2H1A , RBP2-H1

Cellular Localization

Nucleus

Background

This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing resultsi n multiple transcript variants. [provided by RefSeq, Sep 2015]

Database

Research Area

DATA IMAGES

Anti-KDM5B antibody used in IHC (Paraffin sections) (IHC-P). GTX60284

GTX60284 IHC-P Image

IHC-P analysis of rat brain tissue using GTX60284 KDM5B antibody.
Dilution : 1:200

REFERENCE

Application Reference

Xiaobo Wang et al. J Radiat Res 2022; 63 (3) : 331-341 Overcoming radio-resistance in esophageal squamous cell carcinoma via hypermethylation of PIK3C3 promoter region mediated by KDM5B loss.
Application : IHC-P
Reactivity : Human
Submit a Reference

REVIEW

There are currently no reviews for KDM5B antibody (GTX60284). Be the first to share your experience with this product.
Submit a Review
SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399