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KIF3A antibody

Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259
Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259
Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259
Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259

Cat No. GTX11259

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human, Mouse, Rat
Package
50 μl ($279)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:2,000
IHC-P 1:100
Not tested in other applications.

Calculated MW

80 kDa. ( Note )

Positive Control

PC12, rat cerebellum

PROPERTIES

Form

Liquid

Buffer

0.01M PBS pH7.4, 15 mM sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

synthetic peptide corresponding to the C-terminus of mouse KIF3A (amino acids 682-701) conjugated to KLH.

Purification

IgG fraction

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

kinesin family member 3A , FLA10 , KLP-20

Cellular Localization

Cytoplasm, cytoskeleton

Background

The kinesin superfamily (KIFs) of proteins consists of a class of microtubule-dependent motors that plays a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The KIF proteins are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria and mediating transport between the endoplasmic reticulum (ER) and the Golgi complex. KIF3 motor complex is composed of the KIF3A, KIF3B, and KIF3C motor subunits, that associate as heterodimers, in which KIF3B and KIF3C are alternative partners of KIF3A. KIF3A/B has been shown to function in vivo as a motor for the anterograde fast axonal transport of membranebound organelles in neurons. KIF3 plays a crucial role during development. KIF3A-/- and KIF3B-/- mice do not survive beyond midgestation.

Database

Research Area

DATA IMAGES

Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259

GTX11259 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX11259 KIF3A antibody at 0.4 μg/mL.

Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259

GTX11259 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX11259 KIF3A antibody at 0.4 μg/mL.

Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259

GTX11259 IHC-P Image

IHC-P analysis of rat brain tissue using GTX11259 KIF3A antibody at 0.1 μg/mL.

Anti-KIF3A antibody used in IHC (Paraffin sections) (IHC-P). GTX11259

GTX11259 IHC-P Image

IHC-P analysis of rat brain tissue using GTX11259 KIF3A antibody at 0.1 μg/mL.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 279