GeneTex

  • Country / Location Selection

United States (US)

KIR2DL1 antibody [2F9]

Anti-KIR2DL1 antibody [2F9] used in Western Blot (WB). GTX50065

Cat. No. GTX50065

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 2F9

Isotype

 IgG2a

Application

 WB, IP, ELISA

Reactivity

 Human
Package
100 μl ($399)
See all KIR2DL1 products

APPLICATION

Application Note

We recommend the following starting dilutions:
Western Blot: Use at 1:500 ~ 2,000.

Optimal working concentrations should be determined experimentally by the end user.

Calculated MW

39 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human kIR2DL1 (23-223 aa) purified from E. coli

Purification

By protein-G affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 , CD158A , KIR-K64 , KIR221 , KIR2DL3 , NKAT , NKAT-1 , NKAT1 , p58.1

Cellular Localization

Cell membrane

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KIR2DL1 antibody [2F9] used in Western Blot (WB). GTX50065

GTX50065 WB Image

Recombinant human protein kIR2DL1, kIR2DL3, kIR2DS4 and kIR2DL4 (each 50ng per well) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human kIR2DL1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody co

REFERENCE

There are currently no references for KIR2DL1 antibody [2F9] (GTX50065). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for KIR2DL1 antibody [2F9] (GTX50065). Be the first to share your experience with this product.
Submit a Review
SDS
Sodium Azide.pdf
Package List Price ($)
$ 399