GeneTex
United States (US)

KIR2DS2 antibody

Anti-KIR2DS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31949
Anti-KIR2DS2 antibody used in Western Blot (WB). GTX31949

Cat No. GTX31949

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
ICC/IF 20 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

Positive Control

HEK293 Cell Slide(GTX25524) , HEK293 Cell Lysate(GTX27902)

Specificity/Sensitivity

KIR2DS2 antibody is human specific. Multiple isoforms are known to exist.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KIR2DS2 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human KIR2DS2.The immunogen is located within the last 50 amino acids of KIR2DS2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Killer Cell Immunoglobulin Like Receptor, Two Ig Domains And Short Cytoplasmic Tail 2,183Acti,Cd158J,Cd158B,Kir-2Ds2,Nkat-5,Nkat5,Cl-49,Kir2Ds2

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are

Database

Research Area

DATA IMAGES
Anti-KIR2DS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31949

GTX31949 ICC/IF Image

ICC/IF analysis of 293 cells using GTX31949 KIR2DS2 antibody.
Working concentration : 20 μg/ml

Anti-KIR2DS2 antibody used in Western Blot (WB). GTX31949

GTX31949 WB Image

WB analysis of 293 cell lysate using GTX31949 KIR2DS2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Package List Price ($)
$ 329