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KIR3DL1 antibody [6D9A4]

Anti-KIR3DL1 antibody [6D9A4] used in Western Blot (WB). GTX00648
Anti-KIR3DL1 antibody [6D9A4] used in ELISA (ELISA). GTX00648
Anti-KIR3DL1 antibody [6D9A4] used in Western Blot (WB). GTX00648
Anti-KIR3DL1 antibody [6D9A4] used in Flow cytometry (FACS). GTX00648

Cat No. GTX00648

Host

Mouse

Clonality

Monoclonal

Clone Name

6D9A4

Isotype

IgG2b

Application

WB, FACS, ELISA

Reactivity

Human, Rat
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200-1:1000
FACS 1:200-1:400
ELISA 1:10,000
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant fragment of human KIR3DL1 (AA: extra 22-340) expressed in HEK293 cells.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

CD158E1 , KIR , KIR3DL1 , KIR3DL1/S1 , KIR3DL2 , NKAT3 , NKB1 , NKB1B , killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1

Cellular Localization

Cell membrane

Background

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KIR3DL1 antibody [6D9A4] used in Western Blot (WB). GTX00648

GTX00648 WB Image

WB analysis of human KIR3DL1 recombinant protein (AA: extra 22-340) using GTX00648 KIR3DL1 antibody.
Expected MW : 65 kDa

Anti-KIR3DL1 antibody [6D9A4] used in ELISA (ELISA). GTX00648

GTX00648 ELISA Image

ELISA analysis of antigen using GTX00648 KIR3DL1 antibody.
Black : Control Antigen (100 ng)
Purple : Antigen (10ng)
Blue : Antigen (50 ng)
Red Antigen (100 ng)

Anti-KIR3DL1 antibody [6D9A4] used in Western Blot (WB). GTX00648

GTX00648 WB Image

WB analysis of various samples using GTX00648 KIR3DL1 antibody.
Lane 1 : A431 whole cell lysate
Lane 2 : Raji whole cell lysate
Lane 3 : SPC-A-1 whole cell lysate
Lane 4 : K562 whole cell lysate
Lane 5 : HEK293 whole cell lysate
Lane 6 : U937 whole cell lysate
Lane 7 : C6 whole cell lysate

Anti-KIR3DL1 antibody [6D9A4] used in Flow cytometry (FACS). GTX00648

GTX00648 FACS Image

FACS analysis of Jurkat cells using GTX00648 KIR3DL1 antibody.
Green : Primary antibody
Red : Negative control

REFERENCE

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REVIEW

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