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KLC1 antibody

Anti-KLC1 antibody used in Western Blot (WB). GTX54339
Anti-KLC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54339

Cat No. GTX54339

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF

Reactivity

Human, Mouse
Package
100 μl ($379)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

65 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 261-560 of human KLC1 (NP_005543.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

kinesin light chain 1 , KLC , KNS2 , KNS2A

Cellular Localization

Cytoplasmic vesicle,Cytoplasm, cytoskeleton

Background

Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-KLC1 antibody used in Western Blot (WB). GTX54339

GTX54339 WB Image

WB analysis of various sample lysates using GTX54339 KLC1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-KLC1 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54339

GTX54339 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX54339 KLC1 antibody.
Blue : DAPI

REFERENCE

There are currently no references for KLC1 antibody (GTX54339). Be the first to share your publications with this product.

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 379