APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
1:1000 |
1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rat, Xenopus(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 53-82 amino acids from the N-terminal region of human KREMEN1.
Purification
Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
kringle containing transmembrane protein 1 , ECTD13 , KREMEN , KRM1
Cellular Localization
Cell membrane
Background
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein is a component of a membrane complex that modulates canonical WNT signaling through lipoprotein receptor-related protein 6 (LRP6). It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX81373 FACS Image
FACS analysis of A375 cells using GTX81373 KREMEN1 antibody, N-term. Top histogram : negative control Bottom histogram : A375 cells
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GTX81373 WB Image
WB analysis of A375 cell lysate (35ug/lane) using GTX81373 KREMEN1 antibody, N-term.
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REFERENCE
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REVIEW
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