GeneTex
United States (US)

KREMEN2 antibody

GTX31529_2714_WB_20180221_18121410_518.jpg
GTX31529_203_ICC-IF_20180221_18121410_958.jpg

Cat No. GTX31529

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
ICC/IF Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

49 kDa. ( Note )

Positive Control

HeLa Cell Slide(GTX25529) , HeLa Cell Lysate

Specificity/Sensitivity

Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 .The immunogen is located within amino acids 390 - 440 of KREMEN2.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Kringle Containing Transmembrane Protein 2,Krm2,Kremen2

Background

This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Database

Research Area

DATA IMAGES
GTX31529_2714_WB_20180221_18121410_518.jpg

GTX31529 WB Image

WB analysis of HeLa cell lysate using GTX31529 KREMEN2 antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

GTX31529_203_ICC-IF_20180221_18121410_958.jpg

GTX31529 ICC/IF Image

ICC/IF analysis of HeLa cells using GTX31529 KREMEN2 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 339