GeneTex
United States (US)

KSHV LANA2 antibody [CM-A807]

GTX30624_1638_WB_18121410_594.jpg

Cat No. GTX30624

Host Mouse
Clonality Monoclonal
Clone Name CM-A807
Isotype IgG1
Application WB, ICC/IF, IHC-P, IHC-Fr, IP, ELISA
Reactivity Kaposi's sarcoma-associated herpesvirus
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 2 - 4 μg/ml
ICC/IF 1:10 - 1:500
IHC-P 1:10 - 1:500
IHC-Fr 1:10 - 1:500
IP 1:10 - 1:500
ELISA 1:100 - 1:2000
Not tested in other applications.

Specificity/Sensitivity

This is specific for KSHV LANA2 (residues 143-310 epitope recognition).
PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Kaposi's sarcoma-associated herpesvirus

Immunogen

Recombinant LANA2 fusion protein.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

LANA-2 antibody, LANA 2 antibody, Latency-associated nuclear antigen 2 antibody

Cellular Localization

Nuclear

Background

LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist. It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes virus 8. It is found in abundance in the nuclei of cultured cells from KSHV-infected hematopoietic tissues, such as PEL (primary effusion lymphoma) and CD (multicentric Castleman's disease). It does not appear to be expressed in KS (Kaposi's sarcoma) lesions.
DATA IMAGES
GTX30624_1638_WB_18121410_594.jpg

GTX30624 WB Image

WB analysis of infected lysate using GTX30624 KSHV LANA2 antibody [CM-A807].
Lane 1: BCBL-1 cell(KSHV+)
Lane 2: BC-1 cell(KSHV+/EBV+)
Lane 3: BCP-1 cell(KSHV+)
Loading : 30μg
Dilution : 2 μg/ml

Package List Price ($)
$ 319