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KYNU antibody

Anti-KYNU antibody used in IHC (Paraffin sections) (IHC-P). GTX33291
Anti-KYNU antibody used in Western Blot (WB). GTX33291

Cat. No. GTX33291

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all KYNU products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

52 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of human KYNU (NP_001028170.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887706

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

kynureninase , KYNUU , VCRL2

Cellular Localization

Cytoplasm, cytosol

Background

Kynureninase is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranilic acids, respectively. Kynureninase is involved in the biosynthesis of NAD cofactors from tryptophan through the kynurenine pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Database

Research Area

DATA IMAGES

Anti-KYNU antibody used in IHC (Paraffin sections) (IHC-P). GTX33291

GTX33291 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX33291 KYNU antibody.
Dilution : 1:100

Anti-KYNU antibody used in Western Blot (WB). GTX33291

GTX33291 WB Image

WB analysis of various sample lysates using GTX33291 KYNU antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Wang M et al. J Pers Med 2022; 12 (8) Differential Gene Expression and Methylation Analysis of Melanoma in TCGA Database to Further Study the Expression Pattern of KYNU in Melanoma.
Application : WB, IHC-P
Reactivity : Human
Liu Y et al. J Cell Mol Med 2019; A novel role of kynureninase in the growth control of breast cancer cells and its relationships with breast cancer.
Application : IHC-P
Reactivity : Human
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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399