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Kallikrein 11 (cleaved Ile54) antibody

Anti-Kallikrein 11 (cleaved Ile54) antibody used in Western Blot (WB). GTX86927

Cat. No. GTX86927

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μg ($399)
See all Kallikrein 11 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500~1:1000
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Product Note

Kallikrein 11 (cleaved Ile54) antibody detects endogenous levels of fragment of activated Kallikrein-11 resulting from cleavage adjacent to Ile54.

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Kallikrein 11 (35-84).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

KLK11 , PRSS20 , TLSP , kallikrein related peptidase 11 , Kallikrein 11

Cellular Localization

Secreted,Golgi apparatus

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009]

Database

Research Area

DATA IMAGES

Anti-Kallikrein 11 (cleaved Ile54) antibody used in Western Blot (WB). GTX86927

GTX86927 WB Image

WB analysis of HeLa cells treated with etoposide 25uM (24h) lysate using GTX86927 Kallikrein 11 (cleaved Ile54) antibody. The lane on the right is blocked with the synthesized peptide.

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399