GeneTex
United States (US)

Kallikrein 6 antibody

GTX104491_39939_IFA_19011506_945.jpg

Cat No. GTX104491

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application ICC/IF
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
ICC/IF 1:100-1:1000
Not tested in other applications.

Calculated MW

27 kDa. ( Note )

Positive Control

Target recombinant protein

Predict Reactivity

Bovine, Dog, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.88mg/ml

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Bssp antibody, Klk7 antibody, MGC9355 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, KLK6 antibody, serine protease 9 antibody, kallikrein-6 antibody, neurosin antibody, protease M antibody, serine protease 18 antibody, zyme antibody, kallikrein-related peptidase 6 antibody

Cellular Localization

Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]
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Database

Research Area

DATA IMAGES
GTX104491_39939_IFA_19011506_945.jpg

GTX104491 ICC/IF Image

Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed U2OS, using Kallikrein 6(GTX104491) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with GTX11304 (Red) at 1:2000.

SDS
Glycerol.pdf
Thimerosal.pdf