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Kappa Opioid Receptor antibody

Anti-Kappa Opioid Receptor antibody used in Western Blot (WB). GTX108164

Cat No. GTX108164

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($329),
25 μl ($169)
See all Kappa Opioid Receptor products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Positive Control

293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine (pH7), 10% Glycerol

Preservative

0.01% Thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.91 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Kappa Opioid Receptor. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

RRID

AB_1951064

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

opioid receptor kappa 1 , K-OR-1 , KOR , KOR-1 , OPRK

Cellular Localization

Cell membrane; Multi-pass membrane protein

Background

Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for dynorphins. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Database

Research Area

DATA IMAGES

Anti-Kappa Opioid Receptor antibody used in Western Blot (WB). GTX108164

GTX108164 WB Image

Sample (30 ug of whole cell lysate)
A: Hep G2 (GTX27900)
B: Raji
10% SDS PAGE
GTX108164 diluted at 1:1000

REFERENCE

Application Reference

Zhao H et al. Cell Rep 2022; 38 (4) : 110253 Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2.
Cui Y et al. Lipids Health Dis 2019; 18 (1) : 52 κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 329
$ 169