APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
15 μg/ml |
Not tested in other applications.
Calculated MW
Predict Reactivity
Mouse, Rabbit, Bovine, Dog, Hamster, Chicken, Guinea pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda, Turkey(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human Kappa Opioid Receptor.
Purification
Purified by affinity chromatography
Conjugation
Unconjugated
RRID
AB_424955
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
opioid receptor kappa 1 , KOR , KOR1 , OPRK , OPRK1 , Kappa Opioid Receptor
Cellular Localization
Cell membrane
Background
This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]
Database
Research Area
DATA IMAGES
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GTX78007 IHC-P Image
IHC-P analysis of rat brain, purkinje neurons tissue using GTX78007 Kappa Opioid Receptor antibody. Antigen retrieval : Heat-induced antigen retrieval
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REFERENCE
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REVIEW
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