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Kappa Opioid Receptor antibody

Anti-Kappa Opioid Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX78007

Cat No. GTX78007

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human, Rat
Package
25 μg ($289)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 15 μg/ml
Not tested in other applications.

Calculated MW

43 kDa. ( Note )

Predict Reactivity

Mouse, Rabbit, Bovine, Dog, Hamster, Chicken, Guinea pig, Monkey, Bat, Elephant, Gibbon, Gorilla, Horse, Marmoset, Panda, Turkey(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.1% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic 18 amino acid peptide from C-terminus of human Kappa Opioid Receptor.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_424955

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

opioid receptor kappa 1 , KOR , KOR1 , OPRK , OPRK1 , Kappa Opioid Receptor

Cellular Localization

Cell membrane

Background

This gene encodes an opioid receptor, which is a member of the 7 transmembrane-spanning G protein-coupled receptor family. It functions as a receptor for endogenous ligands, as well as a receptor for various synthetic opioids. Ligand binding results in inhibition of adenylate cyclase activity and neurotransmitter release. This opioid receptor plays a role in the perception of pain and mediating the hypolocomotor, analgesic and aversive actions of synthetic opioids. Variations in this gene have also been associated with alcohol dependence and opiate addiction. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study provided evidence for translational readthrough in this gene, and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2017]

Database

Research Area

DATA IMAGES

Anti-Kappa Opioid Receptor antibody used in IHC (Paraffin sections) (IHC-P). GTX78007

GTX78007 IHC-P Image

IHC-P analysis of rat brain, purkinje neurons tissue using GTX78007 Kappa Opioid Receptor antibody.
Antigen retrieval : Heat-induced antigen retrieval

REFERENCE

There are currently no references for Kappa Opioid Receptor antibody (GTX78007). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for Kappa Opioid Receptor antibody (GTX78007). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 289