APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1:1000 |
| 1:50-1:100 |
| 1:10-1:50 |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rat, Rabbit, Bovine, Chicken, Pig(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.09% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
Batch dependent (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
KLH conjugated synthetic peptide between 401-427 amino acids from the C-terminal region of human KCNJ2.
Purification
Protein A purified, followed by peptide affinity purification.
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
potassium voltage-gated channel subfamily J member 2 , ATFB9 , HHBIRK1 , HHIRK1 , IRK1 , KIR2.1 , LQT7 , SQT3
Cellular Localization
Membrane; Multi-pass membrane protein
Background
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX81647 WB Image
WB analysis of human brain lysate using GTX81647 Kir2.1 antibody, C-term.
Loading : 20 μg per lane
Dilution : 1:1000
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GTX81647 FACS Image
FACS analysis of NCI-H460 cells using GTX81647 Kir2.1 antibody, C-term.
Top histogram : negative control
Bottom histogram : NCI-H460 cells
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GTX81647 WB Image
WB analysis of mouse lung tissue lysate (35ug/lane) using GTX81647 Kir2.1 antibody, C-term.
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GTX81647 IHC-P Image
IHC-P analysis of human lung carcinoma using GTX81647 Kir2.1 antibody, C-term.
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REFERENCE
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REVIEW
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