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Kiss1 antibody

Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642
Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642
Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642

Cat. No. GTX37642

Reference 3

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, IHC

Reactivity

 Human, Mouse, Rat, Goat
Package
100 μg ($399)
See all Kiss1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:400-800
IHC Assay dependent
Not tested in other applications.

Calculated MW

15 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

10mM TBS, 0.5% BSA, 25% Glycerol

Preservative

0.015% ProClin 300

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide derived from human Kiss-1:81-145/145AA

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_11163242

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

KiSS-1 metastasis suppressor , HH13 , KiSS-1

Cellular Localization

Secreted

Background

This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]

Database

Research Area

DATA IMAGES

Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642

GTX37642 IHC-P Image

IHC-P analysis of rat brain tissue using GTX37642 Kiss1 antibody.

Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642

GTX37642 IHC-P Image

IHC-P analysis of mouse brain tissue using GTX37642 Kiss1 antibody.

Anti-Kiss1 antibody used in IHC (Paraffin sections) (IHC-P). GTX37642

GTX37642 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX37642 Kiss1 antibody.

REFERENCE

Application Reference

Han Y et al. Gene 2020; 738 : 144488 Local expressions and function of Kiss1/GPR54 in goats' testes.
Application : IHC-P
Reactivity : Goat
Mishra GK et al. Theriogenology 2019; 139 : 167-177 Expression of Kisspeptin and its receptor in the hypothalamus of cyclic and acyclic buffalo (Bubalus bubalis).
Application : IHC
Mishra GK et al. Anim Biotechnol 2018; : 1月10日 Kiss1 and its receptor: molecular characterization and immunolocalization in the hypothalamus and corpus luteum of the buffalo.
Application : IHC-P
Reactivity : Mouse
Submit a Reference

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SDS
Glycerol.pdf
Proclin.pdf
Package List Price ($)
$ 399