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Klotho antibody

Anti-Klotho antibody used in IHC (Paraffin sections) (IHC-P). GTX04566
Anti-Klotho antibody used in IHC (Paraffin sections) (IHC-P). GTX04566
Anti-Klotho antibody used in Western Blot (WB). GTX04566

Cat. No. GTX04566

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all Klotho products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

116 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 150 mM NaCl, 50% glycerol

Preservative

0.02% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthesized peptide derived from human KL(Accession Q9UEF7), corresponding to amino acid residues Y204-A254.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

klotho , HFTC3

Cellular Localization

Cell membrane , Apical cell membrane , Secreted

Background

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Klotho antibody used in IHC (Paraffin sections) (IHC-P). GTX04566

GTX04566 IHC-P Image

IHC-P analysis of human pancreatic cancer tissue using GTX04566 Klotho antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-Klotho antibody used in IHC (Paraffin sections) (IHC-P). GTX04566

GTX04566 IHC-P Image

IHC-P analysis of human pancreatic cancer and adjacent nomal tissue using GTX04566 Klotho antibody.
Antigen retrieval : Heat mediated citrate buffer
Dilution : 1:100

Anti-Klotho antibody used in Western Blot (WB). GTX04566

GTX04566 WB Image

WB analysis of mouse lung tissue lysate using GTX04566 Klotho antibody. The lane on the left was treated with blocking peptide.

REFERENCE

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REVIEW

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Package List Price ($)
$ 399