GeneTex
United States (US)

Klotho antibody

GTX17093_754_IHC-P_20180221_18121410_696.jpg
GTX17093_755_IHC-P_20180221_18121410_664.jpg
GTX17093_753_IHC-P_20180221_18121410_490.jpg
GTX17093_2357_WB_20180221_18121410_333.jpg

Cat No. GTX17093

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

116 kDa. ( Note )

Positive Control

HepG2 Cell Lysate(GTX27900)
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLOTHO antibody was raised against a 16 amino acid synthetic peptide near the center of human KLOTHO.The immunogen is located within amino acids 410 - 460 of KLOTHO.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Klotho,Hftc3,Kl

Background

This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
GTX17093_754_IHC-P_20180221_18121410_696.jpg

GTX17093 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX17093 Klotho antibody.
Working concentration : 20 μg/ml

GTX17093_755_IHC-P_20180221_18121410_664.jpg

GTX17093 IHC-P Image

IHC-P analysis of rat heart tissue using GTX17093 Klotho antibody.
Working concentration : 2.5 μg/ml

GTX17093_753_IHC-P_20180221_18121410_490.jpg

GTX17093 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX17093 Klotho antibody.
Working concentration : 2.5 μg/ml

GTX17093_2357_WB_20180221_18121410_333.jpg

GTX17093 WB Image

WB analysis of HepG2 cell lysate using GTX17093 Klotho antibody.
Working concentration : (A) 1 and (B) 2 μg/ml