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Ku70 antibody [7B1]

Anti-Ku70 antibody [7B1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX66844
Anti-Ku70 antibody [7B1] used in Western Blot (WB). GTX66844
Anti-Ku70 antibody [7B1] used in Immunoprecipitation (IP). GTX66844

Cat. No. GTX66844

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 7B1

Isotype

 IgG

Application

 WB, ICC/IF, IP

Reactivity

 Human, Monkey
Package
100 μl ($459)
See all Ku70 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF 1:50-1:200
IP 1:50-1:200
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.1M Tris-Glycine pH7.4, 150mM NaCl, 50% Glycerol

Preservative

0.2% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified recombinant human Ku70 protein fragments expressed in E.coli.

Purification

Purified by antigen-affinity chromatography

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA

Cellular Localization

Nucleus

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ku70 antibody [7B1] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX66844

GTX66844 ICC/IF Image

ICC/IF analysis of methanol-fixed HeLa cells using GTX66844 Ku70 antibody [7B1].
Dilution : 1:200

Anti-Ku70 antibody [7B1] used in Western Blot (WB). GTX66844

GTX66844 WB Image

WB analysis of HeLa, A549, COS7, and K562 cell lysates using GTX66844 Ku70 antibody [7B1].
Dilution : 1:1000

Anti-Ku70 antibody [7B1] used in Immunoprecipitation (IP). GTX66844

GTX66844 IP Image

IP analysis of HeLa cell lysate using GTX66844 Ku70 antibody [7B1].

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 459