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Ku70 antibody [H-6]

Anti-Ku70 antibody [H-6] used in IHC (Paraffin sections) (IHC-P). GTX03316

Cat. No. GTX03316

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 H-6

Isotype

 IgG1

Application

 IHC-P

Reactivity

 Human
Package
500 μl ($499)
See all Ku70 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 1:50-1:100

Note :

IHC-P
Pretreatment : Citrate Buffer pH 6.0 for 30 min at RT
Not tested in other applications.

Calculated MW

70 kDa. ( Note )

Positive Control

Tonsil

PROPERTIES

Form

Liquid

Buffer

PBS, 0.1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Ku-(p70) is a mouse monoclonal antibody specific for an epitope mapping between amino acids 583-608 at the C-terminus of KU70 of human origin.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA

Cellular Localization

Nucleus

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ku70 antibody [H-6] used in IHC (Paraffin sections) (IHC-P). GTX03316

GTX03316 IHC-P Image

IHC-P analysis of human tonsil tissue section using GTX03316 Ku70 antibody [H-6].

REFERENCE

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REVIEW

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Package List Price ($)
$ 499