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Ku70 antibody

Anti-Ku70 antibody used in Western Blot (WB). GTX70259

Cat No. GTX70259

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB

Reactivity

 Human
Package
100 μl ($329)
See all Ku70 products

APPLICATION

Application Note

For WB: Use at a dilution of 1:2,500. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

70 kDa. ( Note )

Positive Control

HeLa, Raji

PROPERTIES

Form

Liquid

Buffer

Serum diluted with PBS pH7.4

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant antigen containing the amino terminal portion of human Ku70 protein

Purification

Unpurified

Conjugation

Unconjugated

RRID

AB_372046

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

X-ray repair cross complementing 6 , CTC75 , CTCBF , G22P1 , KU70 , ML8 , TLAA

Cellular Localization

Nucleus

Background

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Ku70 antibody used in Western Blot (WB). GTX70259

GTX70259 WB Image

GTX70259 at a 1:2500 dilution staining Ku 70 in A) HeLa whole cell extract and B) Raji whole cell extract by Western Blot (ECL).

REFERENCE

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SDS
PBS.pdf
Package List Price ($)
$ 329