APPLICATION
Product Note
The peptide was used in the production of GTX89026.
PROPERTIES
Form
Lyophilized powder
Buffer
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O.
Preservative
No preservative
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Region/Sequence
YKTEGDEEAEEEQ-C
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
X-Ray Repair Cross Complementing 6 , Ctc75 , Ctcbf , G22P1 , Ku70 , Ml8 , Tlaa , Xrcc6
Background
The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Research Area
REFERENCE
There are currently no references for Ku70 blocking peptide (GTX89026-PEP). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for Ku70 blocking peptide (GTX89026-PEP). Be the first to share your experience with this product.