Kv11.1 antibody

Cat. No. GTX54789

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-P, FACS, IP, LCI
Reactivity	Human, Rat
Package	50 μl ($639)

See all Kv11.1 products

Datasheet
Document

View product citations for antibody GTX54789 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-P	Assay dependent
FACS	Assay dependent
IP	Assay dependent
LCI	Assay dependent

Not tested in other applications.

Calculated MW

127 kDa. ( Note )

Predict Reactivity

Rabbit, Dog(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.6 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide AFLLKETEEGPPATEC corresponding to residues 430-445 ( Extracellular, between S1 and S2 domains) of human KV11.1 (HERG) (Accession : Q12809).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

potassium voltage-gated channel subfamily H member 2 , ERG-1 , ERG1 , H-ERG , HERG , HERG1 , Kv11.1 , LQT2 , SQT1

Cellular Localization

Cell membrane

Background

This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

Database

Gene ID: 3757 KCNH2
UniProt: Q12809 KCNH2

Research Area

DATA IMAGES

GTX54789 FACS Image

FACS analysis of K562 cells using GTX54789 Kv11.1 antibody.
Green : Unstained cell
Black : Cell staining with primary antibody

GTX54789 IP Image

IP analysis of HEK-293 cell lysate using GTX54789 Kv11.1 antibody. Red arrow indicates Kv11.1 while the black arrow shows the IgG heavy chain. WB was performed with the GTX54789 antibody.
Lane 1 : Cell lysate
Lane 2 : Lysate + protein A beads + Anti- Kv11.1 Antibody (GTX54785)
Lane 3 : Cell lysate + protein A beads + Anti-Kv11.1 Antibody (GTX54776)
Lane 4 : Cell lysate + protein A beads + Anti-Kv11.1 Antibody (GTX54789)
Lane 5 : Cell lysate + protein A beads + pre-immune rabbit serum

GTX54789 WB Image

WB analysis of Kv11.1 transfected HEK-293 cell lysates using GTX54789 Kv11.1 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

GTX54789 LCI Image

Live cell imaging analysis of live intact HEK-293 transfected cells using GTX54789 Kv11.1 antibody.
Left panel : Primary antibody
Right panel : Primary antibody preincubated with the negative control antigen
Dilution : 1:25

GTX54789 IHC-P Image

IHC-P analysis of rat heart tissue using GTX54789 Kv11.1 antibody. DAB product is brown and the counterstain is cresyl violet.
Panel A : Transversal section of the atrium wall; note that arterial smooth muscle fibers were not stained (green arrow).
Panel B : Longitudinal section of the myocardium.
Panel C : Section showing myocardium and endocardium (red arrow).

REFERENCE

There are currently no references for Kv11.1 antibody (GTX54789). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for Kv11.1 antibody (GTX54789). Be the first to share your experience with this product.

Submit a Review

SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

50 μl

$ 639

Qty