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Kv4.3 antibody

Anti-Kv4.3 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16642
Anti-Kv4.3 antibody used in Western Blot (WB). GTX16642

Cat. No. GTX16642

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-Fr, IP

Reactivity

Human, Mouse, Rat
Package
50 μl ($639)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-Fr Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

Predict Reactivity

Rabbit(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS pH7.4, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)NEALELTGTPEEEHMGK, corresponding to amino acid residues 451-468 (Intracellular, C-terminus) of human KV4.3 (Accession  : O60577).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

potassium voltage-gated channel subfamily D member 3 , BRGDA9 , KCND3L , KCND3S , KSHIVB , KV4.3 , SCA19 , SCA22

Cellular Localization

Cell membrane,Cell projection, dendrite

Background

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-Kv4.3 antibody used in IHC (Frozen sections) (IHC-Fr). GTX16642

GTX16642 IHC-Fr Image

IHC-Fr analysis of rat hippocampal CA1 region tissue using GTX16642 Kv4.3 antibody. Staining appears in neurons of the CA1 hippocampal region (arrow). Nuclei are stained with DAPI (blue).
Dilution : 1:400

Anti-Kv4.3 antibody used in Western Blot (WB). GTX16642

GTX16642 WB Image

WB analysis of rat brain membrane lysate using GTX16642 Kv4.3 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 639