APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| Assay dependent |
| Assay dependent |
| Assay dependent |
Not tested in other applications.
Calculated MW
Predict Reactivity
Rabbit(>80% identity)
PROPERTIES
Form
Liquid
Buffer
PBS, 1% BSA
Preservative
0.05% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.8 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide (C)NEALELTGTPEEEHMGK, corresponding to amino acid residues 451-468 (Intracellular, C-terminus) of human KV4.3 (Accession : O60577).
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
potassium voltage-gated channel subfamily D member 3 , BRGDA9 , KCND3L , KCND3S , KSHIVB , KV4.3 , SCA19 , SCA22
Cellular Localization
Cell membrane,Cell projection, dendrite
Background
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX16642 IHC-Fr Image
IHC-Fr analysis of rat hippocampal CA1 region tissue using GTX16642 Kv4.3 antibody. Staining appears in neurons of the CA1 hippocampal region (arrow). Nuclei are stained with DAPI (blue).
Dilution : 1:400
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GTX16642 WB Image
WB analysis of rat brain membrane lysate using GTX16642 Kv4.3 antibody preincubated with or without immunogen peptide.
Dilution : 1:200
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REFERENCE
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REVIEW
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