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Kv7.3 / KCNQ3 antibody

Anti-Kv7.3 / KCNQ3 antibody used in IHC (Paraffin sections) (IHC-P). GTX87558

Cat No. GTX87558

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application IHC-P
Reactivity Human
Package
100 μg ($349)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50~1:100
Not tested in other applications.

Calculated MW

97 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Kv7.3 / KCNQ3 (191-240).

Purification

Purified by antigen-affinity chromatography
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

BFNC2,EBN2,KCNQ3,KV7.3,potassium voltagegated channel subfamily Q member 3,Kv7.3,potassium voltage-gated channel subfamily Q member 3

Cellular Localization

Cell membrane

Background

This gene encodes a protein that functions in the regulation of neuronal excitability. The encoded protein forms an M-channel by associating with the products of the related KCNQ2 or KCNQ5 genes, which both encode integral membrane proteins. M-channel currents are inhibited by M1 muscarinic acetylcholine receptors and are activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014]

Database

Research Area

DATA IMAGES
Anti-Kv7.3 / KCNQ3 antibody used in IHC (Paraffin sections) (IHC-P). GTX87558

GTX87558 IHC-P Image

IHC-P analysis of human brain tissue using GTX87558 Kv7.3 / KCNQ3 antibody. The picture on the right is blocked with the synthesized peptide.

REFERENCE
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REVIEW
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Package List Price ($)
$ 349