GeneTex
United States (US)

Kv7.3 / KCNQ3 antibody

Kv7.3-KCNQ3-antibody-GTX87558-IHC-1_18121411_736.jpg

Cat No. GTX87558

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

IHC: 1:50~1:100
ELISA: 1:1000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

96 kDa. ( Note )

Specificity/Sensitivity

Kv7.3/KCNQ3 (Ab-246) Antibody detects endogenous levels of total Kv7.3/KCNQ3 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human Kv7.3 / KCNQ3.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Potassium Voltage-Gated Channel Subfamily Q Member 3,Bfnc2,Ebn2,Kv7.3,Kcnq3

Background

Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs.

Database

Research Area

DATA IMAGES
Kv7.3-KCNQ3-antibody-GTX87558-IHC-1_18121411_736.jpg

GTX87558 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Kv7.3/KCNQ3 (GTX87558) Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 349