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L1CAM antibody [UJ127.11]

Anti-L1CAM antibody [UJ127.11] used in Western Blot (WB). GTX40148

Cat. No. GTX40148

Reference 1

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 UJ127.11

Isotype

 IgG1

Application

 WB, FACS, IP, IHC

Reactivity

 Human
Package
100 μg ($399)
See all L1CAM products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.25-0.5 μg/ml
FACS Assay dependent
IP Assay dependent
IHC Assay dependent
Not tested in other applications.

Calculated MW

140 kDa. ( Note )

Product Note

UJ127.11 may be useful in the diagnosis of embryonic tumours (e.g. neuroblastoma).

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Tissue preparation: Homogenous suspension of human fetal brain

Purification

IgG fraction

Conjugation

Unconjugated

RRID

AB_423954

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

L1 cell adhesion molecule , CAML1 , CD171 , HSAS , HSAS1 , MASA , MIC5 , N-CAM-L1 , N-CAML1 , NCAM-L1 , S10 , SPG1

Cellular Localization

Cell membrane,Cell projection, dendrite

Background

The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Database

Research Area

DATA IMAGES

Anti-L1CAM antibody [UJ127.11] used in Western Blot (WB). GTX40148

GTX40148 WB Image

WB analysis of G361 cells using GTX40148 L1CAM antibody [UJ127.11].
Dilution : 0.5 μg/mL(Lane 1) and 0.25 μg/mL(Lane 2)

REFERENCE

Application Reference

Matsuda A et al. J Proteomics 2013; 85 : 43111 Glycoproteomics-based cancer marker discovery adopting dual enrichment with Wisteria floribunda agglutinin for high specific glyco-diagnosis of cholangiocarcinoma.
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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399