APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
Application |
Recommended Dilution |
Assay dependent |
Assay dependent |
Note :
Sandwich ELISA
Capture: GTX02957, Detection: GTX02983-02 / GTX03013-02 (MT704 for p70) / GTX02956-02 (MT618 for p40).
|
Not tested in other applications.
Calculated MW
Product Note
This antibody is able to detect native and recombinant human IL-23 and recognizes the p19 subunit of the IL-23 heterodimer (p40 + p19). In combination with MT86/221, it detects IL-23 heterodimer (p40 + p19) by sandwich ELISA.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human IL-23
Purification
Protein G purified
From tissue culture supernatant
Conjugation
Biotin
Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
IL23,IL23A,IL23P19,P19,SGRF,interleukin 23 subunit alpha,IL23 p19,il23A
Cellular Localization
Secreted
Background
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX02983-02 ELISA Image
Sandwich ELISA analysis of human IL-23 protein using GTX02957 IL12B / IL12 p40 antibody [MT86 + MT221] as coating antibody and GTX02983-02 L23A / IL23 p19 antibody [MT155] (Biotin) as detecting antibody. Substrate : pNPP
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REFERENCE
There are currently no references for L23A / IL23 p19 antibody [MT155] (Biotin) (GTX02983-02). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for L23A / IL23 p19 antibody [MT155] (Biotin) (GTX02983-02). Be the first to share your experience with this product.