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LAG3 antibody [17B4]

Cat No. GTX33931

Host

Mouse

Clonality

Monoclonal

Clone Name

17B4

Isotype

IgG1

Application

WB, ICC/IF, IHC-Fr, IP, Functional Assay

Reactivity

Human
Package
100 μg ($349)

APPLICATION

Application Note

Functional Assay: Inhibition, Immunohistochemistry frozen sections: 1:150, Immunoprecipitation: 10μg/ml, Western Blot: 5μg/ml

Calculated MW

57 kDa. ( Note )

Specificity/Sensitivity

Recognizes human LAG-3.

PROPERTIES

Form

Liquid

Buffer

PBS containing 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Purification

Protein A-affinity purified.

Purity

≧95% (SDS-PAGE)

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Lymphocyte Activating 3 , Cd223 , Lag3

Background

Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. [provided by RefSeq, Jul 2008]

Database

REFERENCE

REVIEW

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Clone Reference
Package List Price ($)
$ 349