GeneTex
United States (US)

LAIR1 antibody, Internal

GTX88141_2486_WB_18122102_755.jpg
GTX88141_1041_IHC-P_18122102_534.jpg

Cat No. GTX88141

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-3μg/ml
IHC-P 3.75μg/ml
Not tested in other applications.

Calculated MW

31 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88141-PEP).

Specificity/Sensitivity

This antibody is expected to recognize both isoforms (NP_002278.1; NP_068352.1).
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-NDTEDVSQASPSE, from the internal region of the protein sequence according to NP_002278.1; NP_068352.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Leukocyte Associated Immunoglobulin Like Receptor 1,Cd305,Lair-1,Lair1

Background

The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Database

Research Area

DATA IMAGES
GTX88141_2486_WB_18122102_755.jpg

GTX88141 WB Image

WB analysis of human lymph node lysate using GTX88141 LAIR1 antibody, Internal.
Dilution : 2µg/ml
Loading : 35µg protein in RIPA buffer

GTX88141_1041_IHC-P_18122102_534.jpg

GTX88141 IHC-P Image

IHC-P analysis of human tonsil using GTX88141 LAIR1 antibody, Internal.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml

Package List Price ($)
$ 329